08/02/2019 Martin Lenz – Université Paris-Sud

“Why does actomyosin contract ?”

– Martin Lenz –

LPTMS – Université Paris-Sud

The motion of living cells is in large part due to the interaction of semi-flexible actin filaments (F-actin) and myosin molecular motors,
which induce the relative sliding of F-actin. It is often assumed that this simple sliding is sufficient to account for all actomyosin-based
motion. While this is correct in our highly organized striated muscle, we question the application of this dogma to less ordered actomyosin
systems, thus reexamining a cornerstone of our understanding of cellular motion.